You’ve wanted to lose weight for a while, but those stubborn pounds still refuse to shift. And it’s not as if you haven’t tried the ‘traditional’ methods: cutting back on carbs and adding to your exercise regime. But the scales remain mostly the same.
Getting slimmer in midlife and beyond is no easy feat. Is it time, then, to overcome your reluctance and try a weight-loss jab?
Weight-loss drugs are no longer the preserve of Hollywood celebrities. In the UK, they are prescribed as Wegovy and Mounjaro: Mounjaro, aka tirzepatide, is the newer version, which comes with a higher weight-loss potential and may cause fewer side-effects.
According to the Food Foundation, around 8.25 million people have either taken, are currently taking, or are considering trying a weight-loss jab. A UCL study suggests that 1.6 million in Great Britain used them in 2024, and a further 3.3 million people are thinking of going on them over the next year. Is it a case of ‘Can’t beat them, join them’?
So, how do these drugs affect people over 55 in particular? Here are six things you need to know.
They aren’t just for younger people
Dr Sophie Dix is a behavioural neuroscientist, and head of medical affairs at online pharmacist, MedExpress. ‘It’s a common assumption that weight-loss medication is for younger people,’ she says. ‘But one in five of our customers are over the age of 55, and older adults achieve similar weight-loss outcomes to younger adults.’
As we age, hormonal and metabolic changes can make managing our weight more challenging. ‘Joint pain, reduced mobility and changes in muscle mass can also make staying active more difficult than it once was,’ says Dr Dix. ‘For the right person, weight-loss medication can offer valuable support in managing their weight.’
It’s important to stay slim as you age
Carrying excess weight increases your risk of health conditions such as type 2 diabetes, high blood pressure, heart disease and some cancers. ‘It can also put extra pressure on your joints, particularly your knees and hips, which may worsen osteoarthritis and make moving around more difficult,’ says Dr Dix.
The goal isn’t simply to see a lower number on the scales. In later life, maintaining muscle strength, eating well and finding an approach that supports your overall health are just as important.
Consider your other medications
‘If you’re over 55, you may be taking drugs for other health conditions,’ says Dr Dix. ‘Weight-loss treatment can still be suitable, but your healthcare provider needs to consider your overall health and any other medications you take. There are a few things to be aware of. For example, if you take insulin or other diabetes drugs, you may be at an increased risk of low blood sugar. You may need dose adjustment, and to be more closely monitored.’
Exercise against muscle loss
‘As we age, we naturally tend to lose muscle mass and strength, also known as sarcopenia,’ says Dr Dix. This can happen at a faster rate when you're on the jabs. ‘Losing weight can also mean losing some muscle, which is why protecting your muscle health is particularly important during weight loss treatment.
‘Muscle helps you maintain your balance, move around safely and carry out everyday activities independently,’ she says. ‘To help preserve muscle while losing weight, aim to include strength training in your exercise routine, suited to your ability and fitness level.’
NHS guidance recommends activities that strengthen your muscles on at least two days a week. Balance exercise can help further support mobility. ‘You don’t need a gym or expensive equipment,’ says Dr Dix. ‘Choose activities that suit your fitness level and mobility, such as sit-to-stand from a chair, wall push-ups, or weighted squats.’ Tai chi, yoga or simply standing on one leg while brushing your teeth can help with balance.
Eat more protein to stay strong
‘Protein matters in any diet, says Dr Dix. ‘But it’s even more important during weight loss, when a higher intake may help you to preserve lean muscle mass, particularly if you’re also doing the recommended regular strength training.’
Good sources of protein include eggs, Greek yogurt, lean meats, fish, beans, lentils and tofu. ‘Because you’re likely to have less appetite on these medications, always listen to your body,’ she says. ‘Eating too much can make weight-loss medication side effects worse. If you’re feeling too full for a main meal, small, nutrient-dense snacks are a great alternative.’
Vitamin D and calcium are vital for bone health. Clinical advice in the UK recommends that everyone consider a vitamin D supplement in autumn and winter, when levels of sunlight are likely to be naturally much lower.
What about side-effects?
Most people experience mild and short-lived side-effects such as nausea or constipation when starting weight-loss drugs or increasing their dose. ‘Getting plenty of fibre and fluids can keep your bowels moving properly,’ says Dr Dix. ‘If you are feeling nauseous, smaller meals and eating more slowly can help. Make sure you stay hydrated.’