Broncos vs. Seahawks score predictions for Week 6

The Denver Broncos will be home underdogs on Thursday Night Football when they take on the defending Super Bowl champion Seattle Seahawks in Week 6.

Both teams have stumbled out of the gates starting the season 3-2 and have fallen behind their respective division leaders. They winner of this game will keep pace with their rivals, while the other will fall further behind. I would expect the national pundits to be all over the Seahawks in this game with the only love Denver getting is from us inside Broncos Country.

It’s time for the Broncos to be overdogs once again.

Game Overview

Denver Broncos vs. Seattle Seahawks
Thursday, October 15, 2026 at 6:15 P.M. Mile High time
Empower Field at Mile High in Denver, Colorado
ATS Betting Lines: Seattle -2.5
Moneyline Odds: Denver +124 / Seattle -146
Over/Under: 40.5
Note: All odds courtesy of FanDuel Sportsbook.

Collectively, our Mile High Report staff is predicting a narrow Seahawks 23-21 victory over our Broncos on TNF. Three of us actually had Denver winning and two not, but the two negative nellies think the Broncos are heading for a beatdown at home. Shame!

Broncos 23, Seahawks 19

I was pretty close last week to the final score, so we’ll see if we can close in on the target again this week. There are two big question marks for me in this game. The first is how well the Broncos defense can handle JSN and the second has to do with the Broncos interior offensive line and how they fare against the Seahawks strong interior pass rush. Give me a little Bo Nix magic in this one and Denver moves to 4-2. – Tim Lynch

Broncos 23, Seahawks 17

The Broncos thankfully get this Thursday night game at home and it will make all the difference. The defense creates turnovers off of gaffes by the Darnold. Bo Nix capitalizes off of them with a big game from Jaylen Waddle. – Sadaraine

Seahawks 27, Broncos 17

Denver’s primetime matchup versus the defending champion Seattle Seahawks is a tough draw. Their defense is fantastic across the board, are exceptional at limiting opposing passing attacks, and creating turnovers. While their rushing attack on offense is an issue, they have one of the most explosive wide receivers in the NFL in Jaxon Smith-Njigba. Denver’s secondary will be out a few players which makes me wonder if they can limit Smith-Njigba’s impact. With Denver’s offense struggling, I don’t have much faith that Nix and the passing attack will turn things around against a Seahawks defense that is surrendering 150 yards per game through the air. – Chris Hart

Seahawks 31, Broncos 17

We all see the issues with the Broncos. We know that the struggle is real for the offense. Now, the defending champs are coming to Denver and it could get ugly. With key pieces missing on defense, and Bo Nix looking like he has lost confidence, don’t expect much Thursday night. – Adam Malnati

Broncos 24, Seahawks 23

This is one of those games where Nix and Denver find a way. And wearing g the throwback uniforms will give the Broncos a little extra magic on Thursday. The defense does just enough, and the offense does its thing late for the big Thursday night win. – Ian St. Clair

What is your score prediction for the Broncos-Seahawks game? Let us know in the comments section below.