2026 NFL Comeback Player of Year Odds: Patrick Mahomes Heavily Favored

In 2024, San Francisco's Christian McCaffrey suffered from tendinitis in his Achilles and missed eight games due to that injury. He missed even more time battling a right knee issue and ultimately, sat out most of the year. But in 2025, he came back with a vengeance. Last season, CMC amassed a total of 2,126 yards — including 1,202 rushing yards and 10 rushing touchdowns. As a result, the dual-threat running back earned the NFL Comeback Player of the Year award. Now, bettors are asking which player will take home the award at the end of the 2026 season. Here are the odds at DraftKings Sportsbook as of Oct. 15. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Patrick Mahomes: -300Michael Penix Jr.: +1200Kyler Murray: +1200Malik Nabers: +1500George Kittle: +1800Fred Warner: +2000Aaron Donald: +2200Deshaun Watson: +2500Brock Bowers: +2500Travis Hunter: +4000Daniel Jones: +4000Tyreek Hill: +5000 Here's what to know about this oddsboard: The Favorite: Last season, Patrick Mahomes tore his ACL and LCL in the Chiefs' Week 15 game against the Chargers. He underwent surgery the next day, but fast-forward to this season, and he's already proving to be his old self. Through four weeks, he's racked up 1,037 passing yards, nine touchdowns and only two interceptions. And although it's early in the year, K.C. currently boasts a perfect record at 4-0. As a result, Mahomes is the heavy favorite at -300 to win the award. Aaron's Back: Although he missed the Rams' Week 1 game in Australia — a 27-7 loss to the 49ers — Aaron Donald has come out of retirement to join his former team. Donald is a three-time Defensive Player of the Year winner, and his presence will continue to be needed as two-time DPOY winner Myles Garrett will miss some more time with a knee injury. While Donald only has two solo tackles this year, he had a sack on Monday Night against the Bills that was taken back because of a penalty in the secondary. In three games this season, Donald has recorded five total pressures, including four QB hurries and one QB hit as he continues to show flashes of his dominant self.