The Buffalo Bills head west to close out Week 5 against the Los Angeles Rams on “Monday Night Football,” with kickoff set for 8:15 p.m. ET at SoFi Stadium.
Despite a 2-2 start, the Rams remain the favorites to win Super Bowl LXI at +600 on FanDuel Sportsbook, with the 3-1 Bills not far behind at +850. Those odds tell only part of the story heading into Monday’s finale, which could very well be a preview of this season’s Super Bowl, a showdown between the last two NFL MVPs in Josh Allen (2024) and Matthew Stafford (2025).
The Bills will be without one of their top receiving weapons in Week 5, with wideout DJ Moore inactive due to a shoulder injury he aggravated in last week’s loss to the New England Patriots, along with WR Joshua Palmer. The Rams, meanwhile, will have All-Pro defensive tackle Aaron Donald available after missing last week with back soreness. None of those news items should considered a positive for Allen, with the Bills already 3.5-point road underdogs Monday night.
Follow along with Yahoo Sports for live updates, highlights and more as the Rams host the Bills to close out Week 5 on “Monday Night Football,” airing on ESPN.