The Kansas City Chiefs and Seattle Seahawks are two of the most recent Super Bowl winners, and the two star-studded NFL teams are set to meet on Sunday Night Football. Patrick Mahomes and the Chiefs enter the primetime game as one of three undefeated teams remaining.
Our Week 7 NFL picks and predictions are looking ahead at that marquee game and other important matchups. Last week, we finished with an eventful 9-5 record. TBL’s season-long record improves to 53-38-1, with 14 more picks upcoming.
Thursday Night Football kicks off the week’s action with two former high-profile NFL Draft picks with Caleb Williams and Drake Maye battling. The Chicago Bears and New England Patriots were both playoff teams a season ago, and they have similar aspirations this year.
Week 7 features plenty of enticing games ahead. Will we see any major upsets? Which matchups do you have circled for the weekend slate?
MORE: Ranking Super Bowl LXI contenders entering NFL Week 7
NFL Week 7 picks & predictions
Thursday, October 22
New England Patriots at Chicago Bears, 8:15 p.m., Amazon Prime
New England’s offense certainly had its share of struggles during A.J. Brown’s return in Week 6, while the Bears looked dominant with Chicago getting Williams back behind center. We’re riding with Ben Johnson and the powerful Bears passing attack. Pick: Bears 27, Patriots 21
Sunday, October 25
Pittsburgh Steelers vs New Orleans Saints (Paris, France), 9:30 a.m., NFL Network
The NFL’s first-ever game in France features two teams going in different directions. Aaron Rodgers and the Steelers have found a lot of early-season success with Jaylen Warren leading the way on the ground. Meanwhile, New Orleans simply cannot keep Tyler Shough upright with constant pressure. Pick: Steelers 31, Saints 24
San Francisco 49ers at Atlanta Falcons, 1:00 p.m., FOX
Both NFC teams have high-flying offenses with All-Pro running back talents. The slight edge goes to Brock Purdy and Christian McCaffrey as the 49ers aim to improve to 7-0. Pick: 49ers 28, Falcons 27
Cincinnati Bengals at Baltimore Ravens, 1:00 p.m., CBS
Lamar Jackson’s expected return gives Baltimore the edge in a key divisional game. Cincinnati’s had an up-and-down start to 2026 despite the team’s countless offensive weapons. Pick: Ravens 26, Bengals 22
Tampa Bay Buccaneers at Carolina Panthers, 1:00 p.m., FOX
Carolina’s proven through six weeks that they weren’t a fluke playoff team last season. Bryce Young has become one of the top quarterbacks in the league so far, and the Panthers will create further distance from Tampa Bay this week. Pick: Panthers 34, Buccaneers 27
New York Giants at Houston Texans, 1:00 p.m., FOX
C.J. Stroud looks confident behind center as the Texans are finally starting to win games. The Giants are undergoing a QB switch after bringing in J.J. McCarthy from Minnesota recently. We’ll side with Stroud and the ferocious Houston defense. Pick: Texans 27, Giants 21
Indianapolis Colts at Minnesota Vikings, 1:00 p.m., CBS
Minnesota continues to win games to start the 2026 season despite poor offensive consistency. Luckily for the Vikings, they have the chance to face a Colts defense that’s given up over 30 points on three occasions. Pick: Vikings 23, Colts 14
Miami Dolphins at New York Jets, 1:00 p.m., CBS
Geno Smith gets a matchup against one of the remaining winless teams, and that’s huge for a Jets offense aiming to get Breece Hall and Garrett Wilson humming again. Hall’s expected to return to the field after returning to practice this week. Pick: Jets 28, Dolphins 20
Cleveland Browns at Tennessee Titans, 1:00 p.m., CBS
Cleveland’s defense is as good as it gets in the league right now, and that doesn’t bode well for Cam Ward. Meanwhile, Deshaun Watson and the Browns offense has shown they can put up points. Pick: Browns 27, Titans 14
Denver Broncos at Arizona Cardinals, 4:05 p.m., CBS
The Broncos are one of the toughest teams to read, but if Bo Nix plays better this team can certainly make an AFC Championship Game run like a season ago. Arizona enters after a shocking win over the Los Angeles Rams, but it’ll be hard to pull off another upset in Week 7. Pick: Broncos 31, Cardinals 21
Green Bay Packers at Detroit Lions, 4:25 p.m., FOX
The Packers are riding in hot after beating down the Dallas Cowboys in Week 6. However, Detroit hosts this NFC North affair after a bye week, and the Lions offense looks like one of the best in the NFL. Pick: Lions 34, Packers 31
Los Angeles Rams at Las Vegas Raiders, 4:25 p.m., FOX
Sean McVay’s team isn’t playing as advertised, and the loss of Davante Adams is a back-breaker for Los Angeles. The Raiders are playing way above expectations and that continues against the Rams. Pick: Raiders 27, Rams 21
Kansas City Chiefs at Seattle Seahawks, 8:20 p.m., NBC
Seattle’s only issue this season has been playing themselves out of games with mistakes. Kansas City’s played a lot of close games to start the year, but the Seahawks defense finally makes Mahomes uncomfortable on SNF. Pick: Seahawks 27, Chiefs 21
MORE: NFL Week 7 TV schedule: full list of games, start times, TV channels
Monday, October 26
Dallas Cowboys at Philadelphia Eagles, 8:15 p.m., ESPN, ABC
Philadelphia’s season is completely lost with Jalen Hurts’ blood clot issues, but Dallas needs a win in order to get back on track. There’s a strong chance Dak Prescott and Co. break out and put the Cowboys back in the NFC East conversation. Pick: Cowboys 34, Eagles 17
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