The San Francisco 49ers are down another key offensive weapon.
Wide receiver Deebo Samuel left Sunday’s game against the Seattle Seahawks with a hamstring injury in the second half and was quickly ruled out for the rest of the game.
The injury took place in the third quarter as Samuel ran around the edge on a first-down play. As he collapsed, he dropped the ball and fell prone on the field.
the play deebo samuel got injured on
— wok (@wokdior) October 11, 2026
what happened?? pic.twitter.com/fY1E2aVXyH
It was a frightening moment as Samuel’s condition wasn’t initially clear. He was able to eventually stand up and limp off the field.
But he clearly wasn’t right and clutched his right thigh as he made his way to the sidline. The 49ers announced minutes later that he’d been ruled out of the game with a hamstring injury.
Deebo Samuel has been ruled OUT with a hamstring injury, per Tom Rinaldi pic.twitter.com/opryZ0tQux
— FOX Sports: NFL (@NFLonFOX) October 11, 2026