Alzheimer's disease and other forms of dementia can rob a person of their memories and communication skills.
However, there is evidence that the ability to recognise music is retained by people with the condition, even as other cognitive abilities deteriorate.
Two young sisters made this discovery, not through scientific research, but by chance.
Min Luo, 12, and nine-year-old Fei Shan were playing piano for a family friend who has dementia when they noticed a change.
"When we visited him, he would usually be a bit stressed.
"But when we started playing, he would usually sit down, and sometimes he would tap his hand in time with the rhythm or hum along," Min said.
"And I think he really enjoyed that moment and I really treasure it as well."
Min Luo plays to the audience at Korongee. (ABC News: Ebony ten Broeke)
The girls then decided they wanted to share the joy and peace music can bring with others who have the debilitating brain disease.
"Music is like a language that mostly everyone can understand,"
Fei said.
They decided to visit aged care facilities and play for the residents.
The sisters look over their sheet music. (ABC News: Ebony ten Broeke)
'It just makes you feel alive'
At the Korongee Dementia Village, in Hobart's northern suburbs, the girls are performing an afternoon concert.
Some of the residents tap their feet in time with the music, while others nod along.
Nick Dickens is a fan of the sisters and their performances. (ABC News: Ebony ten Broeke)
Resident Nick Dickens is in awe of Fei and Min's musical skill.
"Fantastic, absolutely, they're really talented,"
he said.
"The old stress goes out the window … it just makes you feel alive," he said.
The 75-year-old has frontotemporal and vascular dementia, which has affected his mood and mobility rather than his memory.
Nick Dickens (centre) enjoys the music from the girls, along with the other residents. (ABC News: Ebony ten Broeke)
Once a guitarist in a rock 'n' roll band, Mr Dickens said music was "everything" to him.
"It brings back a lot of memories … and good feelings."
And he said the impact of Min and Fei's concert on his fellow residents at the village was clear.
"I've noticed here a lot of the ones with Alzheimer's, they're sort of in their own world most of the time, but they really respond to music."
The sisters plan to hold a concert to raise money for dementia research.
The residents at Korongee pictured enjoying the music. (ABC News: Ebony ten Broeke)
A dopamine hit and a way to communicate
People with Alzheimer's disease can retain musical memory even when other forms of memory fade.
Fei Shan plays to the crowd. (ABC News: Ebony ten Broeke)
Associate Professor Alison Canty, from the Wicking Dementia Research and Education Centre, said part of the brain responsible for musical memory is quite resilient to the progression of the disease.
"We don't get the same shrinkage or deterioration of the circuits in that region, and we don't know why," she said.
Associate Professor Alison Canty says music releases dopamine, enhancing mood and reducing anxiety and stress. (Supplied: Wicking Dementia Research & Education Centre.)
Associate Professor Canty said even people with the condition who have not spoken for some time may respond to a piece of music they recognise.
"It's kind of another way in, to start interacting and communicating with somebody who's living with dementia,"
she said.
Music can also release the neurotransmitter dopamine.
"It's part of our reward system, and so flooding the brain with dopamine can enhance your mood; it can reduce anxiety, it can reduce stress," Associate Professor Canty said.
There's evidence that the ability to recognise music is retained by people with dementia. (ABC News: Laura Meachim)
In 2025, dementia was named as the leading cause of death in Australia, and by 2065, almost 1.1 million people are predicted to have it.