Oklahoma State’s loss to Tulsa never happened.
The season-opener was a blip. Things weren’t quite in place, it was a bad day, the sun was in their eyes – whatever. The Cowboys got past it to beat Oregon, take out West Virginia and UCF, and now the offense is humming with a 4-1 record and everything to play for.
Houston lost to Texas Tech on a missed two-point conversion, but other than that, it’s been everything it was expected to be in the 5-1 start. But with one Big 12 loss, it has to win this to stay in the conference title chase.
Houston vs Oklahoma State: Quick Hits
- Houston starts a run of three road games in four dates, starting with the biggest remaining showdown on the slate at Utah.
- Oklahoma State starts a run of three road games in four weeks, hosting Colorado next week before going to Iowa State and Kansas State.
- Houston won 39-17 last year, but Oklahoma State has won six of the last ten meetings going back to 1966.
How To Watch Houston vs Oklahoma State
Date: Saturday, October 17, 2026
Game Time: 7:30 PM ET
TV: FOX
Location: TDECU Stadium, Houston, TX
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Why Oklahoma State Will Win
It took a little bit to get up to speed, but the Oklahoma State offense has turned into everything the fan base could’ve asked for, and more, averaging well over 500 yards and 45 points per game over the last four.
It’s the No. 1 offense in the Big Ten behind a line that’s great at keeping teams out of the backfield and putting the pressure on defense. It’s a relentless style with the balance to tear off yards in chunks, but …
Why Houston Will Win
As good as the Oklahoma State offense is, it’s not great on third downs. It’s got midrange pop, and it operates on speed and tempo, but it’s only connecting on 34% of its tries.
How do you handle what the Cowboys do? You control the narrative. You do that by dominating third downs, and that’s what Houston does. It’s No. in the nation, converting 63% of its chances with a balanced attack that can adapt to any situation.
Houston vs Oklahoma State Prediction, Betting Lines
Oklahoma State might be splashier and fun, but Houston will be consistently tough on both sides of the ball at home. The Cougars will get to the Cowboy running game first, and from there, it won’t allow the short passes to turn into anything big.
Houston looked like a real Big 12 player last week in the win over Kansas State. This week it takes another step to being considered a true threat to get to the College Football Playoff.
Houston 34, Oklahoma State 28
Latest Consensus Line: Houston -4.5, o/u: 62.5
ATS Confidence (out of 5): 2.5
Must See Rating (out of 5): 4
Consensus line based on BetMGM, Caesars, DraftKings, and FanDuel. Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.