Köln come into this game off the back of a 1-0 loss away at Frankfurt following a positive win in their last home match two weeks ago against rivals Borussia Mönchengladbach.
For Schalke, it was a poor 1-0 defeat at home to Mainz which left the Ruhr side waiting for their first win at home this season.
Köln will look to make it back-to-back home wins for the first time since January this year and to push up the table and improve on their 12th-place position.
FC Köln (4-2-3-1):
Schwäbe - Sebulonsen, Simpson Pusey, Lochosvili, Sosa - Krauss, Jóhannesson - Maina, Moore, El Mala - Bülter
Schalke (3-4-2-1):
Karius - Kuruçay, Katić, Becker - Gantenbein, El-Faouzi, Tanaka, Gosens - Dina Ebimbe, Aouchiche - Chan Hwang