Twenty-one pupils and a teacher were killed on Thursday after a roof collapsed at a school in the northwest Pakistani city of Peshawar, a hospital official said.
Asim Khan from Peshawar's Lady Reading Hospital confirmed the toll to AFP, adding that over 30 people were injured, with six believed to be in a critical condition.
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Pakistan's Prime Minister Shehbaz Sharif in a statement expressed "deep sorrow and grief over the loss of precious lives".
"The Prime Minister extends his condolences to the bereaved families and prays for them to have the strength and patience to bear this irreparable loss," the statement said.
In June this year more than a dozen children were killed in a roof collapse at a tutoring centre in the eastern city of Lahore.
In 2025, 27 people were killed and 10 injured when a five-storey building collapsed in the impoverished area of Lyari in the southern city of Karachi.